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About Dave Asprey. Dave Asprey is founder of Bulletproof, and creator of the widely-popular Bulletproof Coffee. Oz, and many more. These products are not intended to diagnose, treat, cure, or prevent any disease. For example, studies investigating the effects of L-arginine on blood pressure have used doses of 6—30 grams per day for 2—24 weeks 22 , In those with erectile dysfunction, research has suggested that supplementing daily with 1.
L-arginine may also be given intravenously to pregnant women with high blood pressure in the clinical setting 22 , This is explained in greater detail later in this article.
L-arginine may interact with certain medications, including 22 :. Additionally, L-arginine may interact with certain supplements and substances, including 22 :. Keep L-arginine supplements in a cool, dry area. Avoid exposing the supplement to heat or moisture. L-arginine supplementation during pregnancy is typically prescribed and monitored by a healthcare provider for a specific reason, such as preeclampsia or the risk of preeclampsia and intrauterine growth restriction IUGR 22 , This increased need may not be met through diet, especially in women living in low-resource settings without access to protein-rich foods Additionally, although the increased demand for arginine during pregnancy can be provided through diet, protein or individual amino acid supplements may be necessary under certain circumstances.
This may include women who follow restrictive diets or are experiencing severe nausea and vomiting during pregnancy , rendering them unable to meet demands through dietary intake. However, supplements during pregnancy should always be approved and monitored by a healthcare provider.
If you are pregnant and interested in taking supplemental L-arginine, consult your healthcare provider for advice. L-arginine supplements have not been researched in breastfeeding women. The safety of L-arginine has been demonstrated in many populations, including pregnant women and older adults. However, some people, including those with conditions that affect the liver or kidneys, should avoid L-arginine L-arginine supplements are sometimes used in children in the clinical setting and deemed safe when prescribed in appropriate doses.
Yet, arginine supplementation in children should always be monitored by a healthcare provider. This advice is extremely important to follow, as giving a child too high a dose of L-arginine may result in serious side effects and can even be fatal After consumption, your gut and liver rapidly metabolize L-arginine before it has the chance to reach systemic circulation.
For this reason, some argue that L-citrulline , a precursor to L-arginine, may be a better choice for increasing arginine levels. L-citrulline is an amino acid that may be used as an alternative to L-arginine when taken as a supplement.
L-citrulline is converted into L-arginine through a series of enzymatic reactions that take place primarily in your kidneys Research shows that L-citrulline supplements can raise body levels of L-arginine. In fact, some studies show that L-citrulline is more effective at increasing arginine levels than L-arginine supplements 29 , 30 , 31 , 32 , The recommended range is, however, between grams in a day.
If you overdose, there are side-effects like diarrhoea, nausea or weakness. So, the best way out is to start with a lower dose, which makes the initial L-Arginine cut at grams initially. Now, GH stimulation is a benefit of arginine and it is important for bodybuilders since it burns fat, increases muscle growth, improves cell repair, and has a positive effect on metabolism too.
So, what is the solution? It is to take a high dosage up to grams of arginine before bed. While you are sleeping, you can enjoy the benefit of increased growth hormone production and the other benefits as I mentioned before. The bottom line is that arginine improves production of growth hormones when not taken around the workout time.
You can also take the arginine dosage first thing in the morning to feel more energetic and improve your blood circulation, for example. During the day, you can take a mg dose to activate the nitric oxide production inside the body.
The best way to have it is to mix 3 scoops of arginine powder in water and you can repeat this mix times in a day, depending on your workout schedule. Do not mix it with other glycaemic drinks like flavoured water or juices. Before the bedtime, you can add 2 scoops of arginine powder in water and have it half an hour before going to bed, on an empty stomach.
To enjoy the full benefits of arginine during the night, it is crucial not to have it with glycaemic drinks, food, or even other amino acids or supplements. The research to support supplemental arginine as a performance enhancer is limited by itself but is often combined with other supplements such as BCAAs and glutathione.
Results are conflicting but show significant positive outcomes than without supplementation. Arginine injection absolutely contraindicated in patients with known arginine hypersensitivity or a hypersensitivity to any components of the product. There is NO standard doing for L-Arginine. Dosing typically varies depending on reason for administration: performance, sexual dysfunction, immunity protection. L-Arginine should be taken continuously for 2 or 3 months to gain the most benefit.
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